GLB1 and FOS

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GLB1	FOS
Description		galactosidase beta 1	Fos proto-oncogene, AP-1 transcription factor subunit
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Vacuole Golgi Apparatus Azurophil Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen	Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Cytosol Membrane Protein-DNA Complex Transcription Factor AP-1 Complex Neuron Projection
	Molecular Function	Beta-galactosidase Activity Protein Binding Galactoside Binding Protein Homodimerization Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Identical Protein Binding Protein-containing Complex Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Glycosaminoglycan Catabolic Process Glycosphingolipid Metabolic Process Galactose Catabolic Process Keratan Sulfate Catabolic Process Cellular Carbohydrate Metabolic Process Response To Cortisone Response To Thyroglobulin Triiodothyronine	Conditioned Taste Aversion DNA Methylation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Inflammatory Response Transforming Growth Factor Beta Receptor Signaling Pathway Nervous System Development Female Pregnancy Aging Response To Cold Response To Xenobiotic Stimulus Response To Light Stimulus Response To Gravity Response To Toxic Substance Sleep Cellular Response To Extracellular Stimulus Response To Lipopolysaccharide Response To Progesterone Cellular Response To Hormone Stimulus Response To Cytokine Cellular Response To Reactive Oxygen Species Response To Immobilization Stress Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Corticosterone Response To CAMP SMAD Protein Signal Transduction Cellular Response To Cadmium Ion Cellular Response To Calcium Ion Positive Regulation Of Neuron Death Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways		Glycosphingolipid metabolism Keratan sulfate degradation HS-GAG degradation MPS IV - Morquio syndrome B Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation	Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) FCERI mediated MAPK activation Activation of the AP-1 family of transcription factors Interleukin-4 and Interleukin-13 signaling TP53 Regulates Transcription of DNA Repair Genes Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs		Lactose	Pseudoephedrine Nadroparin
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Aspartate aminotransferase levels ( 33547301) Asthma ( 31361310 31959851 30929738 34103634 32296059 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 31036433 30929738) Atopic dermatitis ( 23042114) Celiac disease ( 22057235) Eosinophil counts ( 29403010 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hepatocellular carcinoma ( 21105107) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233) Periodontal microbiota ( 22699663)
Interacting Genes		12 interacting genes: CSNK2B CTSA DNAJB1 FOS GOLM1 NEU1 OGT PLK1 SLC10A6 SLC30A2 SLC7A1 TK1	123 interacting genes: AKAP5 ANP32E APP AQP1 ARFGAP1 ARL6IP4 ATF2 ATF3 ATF4 ATF7 ATP5ME BATF BCL3 CABP1 CARM1 CCDC120 CCND1 CEBPA CEBPE CEBPG CENPO CFAP57 CLU COPS4 CREB5 CREBBP CSNK2A1 CSNK2A2 CYTH4 DDIT3 DNMT3L DYNLT3 EEF1D ELK1 ELK4 ENKD1 EPHB2 ETS1 ETS2 FHL3 GAMT GATA4 GLB1 GNG11 GRHPR GTF2E2 GTF2F1 GTF2F2 HMGB1 HNF1A HSPA1A JUN JUNB JUND KDM2A KDM2B LMNA LMO3 LUZP4 MAF MAFB MAFF MAP1B MAP3K7 MAPK1 MAPK3 MAPK7 MDM2 MITF MTERF4 NACA NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NEFM NELFB NFATC3 NFKB1 OPTN PIN1 PML POLR2E PRKAA2 PRKACA PRKAR2A PSMC5 RB1 RELA RPS6KA1 RPS6KA2 RPS6KA4 RUNX1 RUNX2 SCHIP1 SET SIRT1 SMAD3 SMARCD1 SPI1 SRA1 STAT1 SUMO1 SUMO2 SUMO3 SUMO4 TAF1 TBP TENT5B TP53 TRO TSC22D3 TSPAN2 UBE2D1 UBE2I UBE2L3 UBR1 USF1 USF2 VDR XBP1 ZNF133
Entrez ID		2720	2353
HPRD ID		01975	01275
Ensembl ID		ENSG00000170266	ENSG00000170345
Uniprot IDs		B7Z6Q5 P16278	P01100 Q6FG41
PDB IDs		3THC 3THD 3WEZ 3WF0 3WF1 3WF2 3WF3 3WF4	1A02 1FOS 1S9K
Enriched GO Terms of Interacting Partners?
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