HSPB7 and CEP76

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSPB7	CEP76
Description		heat shock protein family B (small) member 7	centrosomal protein 76
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cajal Body Actin Cytoskeleton Aggresome	Centrosome Centriole Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Filamin Binding	Protein Binding
	Biological Process	Response To Unfolded Protein Heart Development Regulation Of Heart Contraction	Regulation Of Centriole Replication
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Arterial stiffness index ( 31235810) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erectile dysfunction ( 30583798) Hypertrophic cardiomyopathy ( 33495596 33495597) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Systolic blood pressure ( 28739976)
Interacting Genes		20 interacting genes: APP BAG3 C22orf15 CEP76 DDIT4L DYNLT1 FLNA GUCD1 HSPB8 PDLIM7 PIP4K2B PLEKHF2 PRDM14 REL RERE SF3B4 SYCE1 TCF4 TEPSIN TRIM23	106 interacting genes: AKAP7 AKT1 ANKRD36 ASH2L BANP C22orf39 CABP5 CACNB3 CAPN3 CAVIN3 CCDC92 CCNK CDK18 CENPI CIR1 COIL CRYBA4 CSNK1G1 CUTC CWF19L2 DCTD DDX6 DEAF1 DMTN DVL3 DZIP1L EAF1 EIF1AD EP400P1 ERCC3 FAM90A1 GDAP2 GFAP GORASP2 HSF2 HSPB7 ILVBL IQUB KDM1A KDM4D KIAA1143 KIFBP KLHDC4 L3MBTL2 LATS1 LNX1 MAGEA11 MBD3 MFAP1 MISP MLH1 MYOZ1 NEK6 NFYC NHLRC2 NME5 PAICS PARD6B PATZ1 PDGFRB PDRG1 PDZD4 PDZD7 PIN1 PKP1 PLA2G6 PLCB1 POM121 RADIL RALGPS1 RBM41 RIPPLY3 RNF128 RPL9 SALL2 SCNM1 SEC11A SH2D4A SINHCAF SMG9 SPG21 STK26 SUOX TBC1D27P TCEA2 TCEANC TCF19 TFAP2D THRA TOB2 TSPOAP1 TSSC4 TTC21A TTLL10 TUFT1 TXNDC9 VEZF1 WDFY3 YY1 ZBTB24 ZBTB4 ZMAT2 ZNF185 ZNF653 ZNF76 ZNF85
Entrez ID		27129	79959
HPRD ID		13684	12694
Ensembl ID		ENSG00000173641	ENSG00000101624
Uniprot IDs		Q9UBY9	B4DP81 Q8TAP6
PDB IDs
Enriched GO Terms of Interacting Partners?
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