GJB5 and LRP10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GJB5	LRP10
Description		gap junction protein beta 5	LDL receptor related protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Connexin Complex Integral Component Of Membrane	Plasma Membrane Clathrin-coated Pit Membrane Integral Component Of Membrane
	Molecular Function	Gap Junction Channel Activity Protein Binding	Low-density Lipoprotein Particle Receptor Activity Protein Binding
	Biological Process	Cell-cell Signaling Epidermis Development Transmembrane Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Morphogenesis Epididymis Development	Lipid Metabolic Process Lipid Transport Endocytosis Inner Ear Development
Pathways		Gap junction assembly	Retinoid metabolism and transport
Drugs
Diseases
GWAS		BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Narcolepsy ( 23459209) Sleep duration (short sleep) ( 30846698) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Visceral adipose tissue adjusted for BMI ( 22589738)	Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Neutrophil count ( 32888494)
Interacting Genes		45 interacting genes: APOL2 APOL3 AQP1 C1GALT1 C4orf3 COMT CTXN3 CYB5B DNALI1 ERG28 FAM3C GSK3B IGFBP5 JAGN1 LMNA LPAR3 LRP10 MED1 MIP MS4A13 MYL2 NAPB PCGF2 PGAP2 PLPP4 PLPP6 PNLIPRP1 RPRM RTP2 SEC22A SEC22B SERP1 SLC30A2 SLC38A7 SLC41A1 SLC41A2 SMIM1 TM4SF4 TMEM128 TMEM60 TMEM86A TMEM97 TRIM2 TSPO2 VSTM1	24 interacting genes: C16orf92 CISD2 EBP FAM209A GGA3 GJB5 GOLM2 GORAB HTRA1 LMNA MFSD14B MGST3 MRPS18B NGDN NOTO PDCD1LG2 PLEKHO1 SLC10A1 SLC14A2 SMIM1 ST6GALNAC6 TMEM179B TMEM237 TMEM243
Entrez ID		2709	26020
HPRD ID		06840	14311
Ensembl ID		ENSG00000189280	ENSG00000197324
Uniprot IDs		A0A654IE64 O95377	Q7Z4F1
PDB IDs
Enriched GO Terms of Interacting Partners?
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