DAPP1 and FAIM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		DAPP1	FAIM
Description		dual adaptor of phosphotyrosine and 3-phosphoinositides 1	Fas apoptotic inhibitory molecule
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GO Annotations	Cellular Component	Cytosol Plasma Membrane	Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding
	Biological Process	Protein Dephosphorylation Signal Transduction	Apoptotic Process I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neurogenesis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs		Inositol 1,3,4,5-Tetrakisphosphate
Diseases
GWAS		Red cell distribution width ( 32888494) Stroke ( 32693751)	Blood protein levels ( 30072576) Male-pattern baldness ( 28196072)
Interacting Genes		23 interacting genes: BTK CNDP2 ERBB3 FAIM FCHSD2 FXN GSTCD HSD3B7 HSPA1A LCK LYN MAP4K1 MGARP MYLIP PLAGL2 PLCG1 PLCG2 RBP7 RPL23 SRC TM4SF19 TNFAIP1 ZNHIT1	9 interacting genes: CDR2L DAPP1 INCA1 LHX3 LMNA SPRY2 TRIM62 ZNF16 ZRANB1
Entrez ID		27071	55179
HPRD ID		05773	16874
Ensembl ID		ENSG00000070190	ENSG00000158234
Uniprot IDs		J3KNB3 Q9UN19	Q9NVQ4
PDB IDs		1FAO 1FB8	2KW1 3MX7
Enriched GO Terms of Interacting Partners?
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