ANKRD1 and DNAJB6

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		ANKRD1	DNAJB6
Description		ankyrin repeat domain 1	DnaJ heat shock protein family (Hsp40) member B6
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol I Band	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	P53 Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding	ATPase Activator Activity DNA Binding Protein Binding Heat Shock Protein Binding Protein Folding Chaperone Unfolded Protein Binding Chaperone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Protein Kinase C Signaling Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Cellular Response To Xenobiotic Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of DNA Biosynthetic Process	Protein Folding Actin Cytoskeleton Organization Extracellular Matrix Organization Regulation Of Protein Localization Protein Localization To Nucleus Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Chaperone-mediated Protein Folding Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways		PPARA activates gene expression	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 29617998) Refractive error ( 32231278)	Body mass index ( 28552196) Retinal detachment or retinal break ( 31816047) Waist circumference ( 28552196)
Interacting Genes		23 interacting genes: APPL1 ARHGDIB ASH2L CASQ2 CDCA7L DNAJB6 DST DYSF LRPPRC MAPRE3 MEOX2 MYBPC1 MYL1 MYOM2 MYPN NAGK REPS1 SPANXN2 TRIM55 TRIM63 TTN TULP3 ZNF446	23 interacting genes: ANKRD1 APP ASAP1 BRMS1 CAND2 DYSF EPHB4 KRT18 MAP3K1 MLF1 MRTO4 MYBPC1 MYOM1 PGM1 PIK3CA POLR1D PTEN SGCG SKAP2 SUPT6H TTN TUBGCP3 USP8
Entrez ID		27063	10049
HPRD ID		10647	07107
Ensembl ID		ENSG00000148677	ENSG00000105993
Uniprot IDs		A0A384NYH5 Q15327	A0A0J9YX62 O75190
PDB IDs			6U3R 6U3S 7JSQ
Enriched GO Terms of Interacting Partners?
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