PELP1 and TOM1L1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PELP1	TOM1L1
Description		proline, glutamate and leucine rich protein 1	target of myb1 like 1 membrane trafficking protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Transcriptionally Active Chromatin MLL1 Complex	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Transcription Factor Binding SUMO Binding Protein N-terminus Binding ATPase Binding	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Estrogen Stimulus	Signal Transduction Protein Transport Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol PTK6 Expression
Drugs
Diseases
GWAS		Eosinophil counts ( 29403010)	Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Systolic blood pressure ( 34074324) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		25 interacting genes: AR BAG6 BCAS3 BLOC1S1 CREBBP EP300 ESR1 ESR2 H1-1 H2AC20 H2BC21 H3-3A H4C1 HGS NFKB1 NR3C1 PTEN RB1 SMAD9 SNCA SRC STAT3 SUMO2 TOM1L1 TP53	29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP
Entrez ID		27043	10040
HPRD ID		10144	05266
Ensembl ID		ENSG00000141456	ENSG00000141198
Uniprot IDs		B4DEX7 B4DR36 C9JFV4 E7EV54 Q8IZL8	O75674 Q8NI65
PDB IDs			3RRU
Enriched GO Terms of Interacting Partners?
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