ATP2C1 and GPR35

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		ATP2C1	GPR35
Description		ATPase secretory pathway Ca2+ transporting 1	G protein-coupled receptor 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Integral Component Of Membrane Integral Component Of Golgi Membrane Golgi Cisterna Membrane Cis-Golgi Network Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	P-type Calcium Transporter Activity ATP Binding P-type Ion Transporter Activity ATP Hydrolysis Activity Metal Ion Binding P-type Manganese Transporter Activity	G Protein-coupled Receptor Activity C-X-C Chemokine Receptor Activity
	Biological Process	Calcium Ion Transport Manganese Ion Transport Cellular Calcium Ion Homeostasis Epidermis Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Actin Cytoskeleton Reorganization Golgi Calcium Ion Homeostasis Golgi Calcium Ion Transport Ion Transmembrane Transport Positive Regulation Of Golgi To Plasma Membrane Protein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Calcium Ion Transmembrane Transport Manganese Ion Transmembrane Transport Trans-Golgi Network Membrane Organization	Cytoskeleton Organization G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Chemokine-mediated Signaling Pathway Negative Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Neuronal Action Potential
Pathways		Ion transport by P-type ATPases	Class A/1 (Rhodopsin-like receptors)
Drugs		Enflurane Isoflurane Methoxyflurane Desflurane Sevoflurane Calcium	Furosemide Pyrantel Kynurenic Acid
Diseases
GWAS		Refractive error ( 32231278) Restless legs syndrome ( 29029846) Waist circumference ( 28552196)	Ankylosing spondylitis ( 23749187) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 25489960) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Pediatric autoimmune diseases ( 26301688) Sclerosing cholangitis and ulcerative colitis (combined) ( 22821403) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		4 interacting genes: F2RL1 GGCX GPR35 GTF2IRD1	59 interacting genes: ABHD14A ADGRB1 AIG1 APH1A ATP1A1 ATP2C1 AUP1 B3GAT3 B4GALT2 BNIP1 CANX CD81 CH25H CMTM3 CRHR2 ERGIC3 FLRT1 FTH1 GHITM GJC2 GPR146 GPR161 HLA-A KCNJ4 KDELR1 LSS MCOLN1 MSMO1 NPC1 NSDHL OSTC PLD3 PLLP PLXDC1 PPP1R3F RTN3 RTN4 SCARB1 SDHD SELENOK SLC15A4 SLC2A1 SLC31A2 SLC37A1 SLC37A4 SLC45A4 SLC8A2 SLC9A7 SPART SYNGR2 SYT11 TMEM161A TMEM94 TSPAN7 VPS25 VTI1B YIF1B ZDHHC3 ZFAND1
Entrez ID		27032	2859
HPRD ID		05089	16003
Ensembl ID		ENSG00000017260	ENSG00000178623
Uniprot IDs		B4E295 B4E2Q0 P98194	A8K2J1 B2RA17 Q9HC97
PDB IDs
Enriched GO Terms of Interacting Partners?
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