GJA8 and YIF1A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GJA8	YIF1A
Description		gap junction protein alpha 8	Yip1 interacting factor homolog A, membrane trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Connexin Complex	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Gap Junction Channel Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Lens Development In Camera-type Eye Cell-cell Signaling Transmembrane Transport Gap Junction-mediated Intercellular Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport
Pathways		Gap junction assembly	XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Retinopathy x type 2 diabetes interaction ( 32541925) Triglyceride levels ( 34074324)	Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		121 interacting genes: ABL1 ACKR2 APOA2 APOD APOL3 AQP4 ARL6IP6 ATP6V0B C1GALT1 C2CD2L C3orf52 CCDC167 CCL4 CD53 CIAO2A CLDN19 CLDN4 CLEC1A CLN6 COX20 CTXN3 CXCL16 CYBC1 CYP4F2 DEFB121 DOLK ERMP1 FDFT1 FXYD6 GIMAP1 GIMAP5 GJB2 GPR108 GPR151 GPR61 GUCA2A IGFBP5 INSIG2 ITGAM KIR2DL3 LAPTM4B LAT LEPROTL1 LHFPL5 MAL MALL MARCHF2 MFSD11 MFSD6 MGST2 MIP MS4A13 ORMDL2 OTOP2 P2RY13 PGAP2 PLN PMP22 PNLIPRP1 PRAF2 PROKR2 PTPRN QRFPR REEP6 RNF152 RUSF1 RXFP4 S1PR5 SCARF1 SEC22B SEC22C SEC23A SFTPC SLC13A2 SLC13A5 SLC16A12 SLC16A13 SLC16A3 SLC30A3 SLC35A4 SLC35F1 SLC35F6 SLC38A4 SLC38A7 SLC39A2 SLC39A7 SLC39A9 SLC52A1 SLC66A1 SLC66A2 SLC8A3 SMCO4 SMIM1 STX1B STX8 THSD7B TJP1 TMBIM6 TMEM100 TMEM107 TMEM121 TMEM128 TMEM147 TMEM182 TMEM239 TMEM242 TMEM243 TMEM42 TMEM45A TMEM60 TMEM65 TMEM72 TMEM86B TSPAN33 TWSG1 UBXN8 UNC93A UPK1B VAMP5 YIF1A YIPF6	82 interacting genes: ADAM17 APOA5 AQP6 BNIP2 C4orf3 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GNL1 GPR37 GPR42 GPX8 HEATR1 JOSD2 KAT5 KCNK5 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MRPL18 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PRIM1 PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35C2 SLCO2B1 SNX10 SNX11 SNX2 STARD10 STIP1 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 WDR74 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27
Entrez ID		2703	10897
HPRD ID		02939	06755
Ensembl ID		ENSG00000121634	ENSG00000174851
Uniprot IDs		P48165 X5D7G1	A6NGW1 A8K509 O95070
PDB IDs
Enriched GO Terms of Interacting Partners?
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