AMPD1 and AMPD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AMPD1	AMPD3
Description		adenosine monophosphate deaminase 1	adenosine monophosphate deaminase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Region Cytosol Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	AMP Deaminase Activity Protein Binding Myosin Heavy Chain Binding Identical Protein Binding Metal Ion Binding	AMP Deaminase Activity Protein Binding Metal Ion Binding
	Biological Process	IMP Biosynthetic Process Response To Organic Substance IMP Salvage AMP Metabolic Process	IMP Biosynthetic Process AMP Catabolic Process IMP Salvage AMP Metabolic Process
Pathways		Purine salvage	Neutrophil degranulation Purine salvage
Drugs
Diseases
GWAS		Autism ( 24189344) Body size at age 10 ( 32376654)	Apolipoprotein A1 levels ( 32203549) Cutaneous melanoma or hair colour ( 32341527) Diastolic blood pressure ( 27841878) Glycated hemoglobin levels ( 34059833) Haemorrhoidal disease ( 33888516) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Neutrophil percentage of white cells ( 32888494) Nonunion in individuals with fractures ( 30680360) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 27841878) Total cholesterol levels ( 30498476) Waist-hip index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: AMPD2 AMPD3 C1QTNF9 MYH2	2 interacting genes: AMPD1 KCNIP1
Entrez ID		270	272
HPRD ID		00040	00041
Ensembl ID		ENSG00000116748	ENSG00000133805
Uniprot IDs		P23109	Q01432
PDB IDs
Enriched GO Terms of Interacting Partners?
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