SEC22A and SPAG4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SEC22A	SPAG4
Description		SEC22 homolog A, vesicle trafficking protein	sperm associated antigen 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nuclear Envelope Integral Component Of Nuclear Inner Membrane Cytoplasm Cytoskeleton Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	Transporter Activity Protein Binding	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport	Nuclear Envelope Organization Spermatogenesis Cell Differentiation
Pathways		COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)	Blood protein levels ( 28240269) Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		106 interacting genes: ADGRG3 AQP6 ASGR2 ATP6AP2 BIK BNIP3 C10orf67 C16orf54 C16orf92 CALN1 CD207 CD300A CD7 CD74 CISD2 CLEC10A CLEC12B CLEC2D CLEC7A CREB3L1 CYB561 CYBRD1 DDIT4L DIABLO DTX2 EDA ELOVL4 ERLIN1 ERVFRD-1 FAM174A FAM209A FATE1 FUT3 GAD2 GGT6 GJB5 GJB6 GPR37L1 GRAMD2B HAVCR2 HCST HSD17B11 ICAM3 KCNJ2 LDAF1 LDLRAD1 LHFPL5 LMNA LPAR6 LRRC25 LSMEM2 MCOLN1 MFF MGST2 MINAR1 MS4A14 MS4A3 MS4A4A MSR1 OPRM1 PACC1 PEX12 PHB PTGES RASGRP4 RETREG3 RILPL1 RNASEK RNF144A RNF19B RNF5 SAR1A SCN3B SDHAF2 SFTPC SLC14A2 SLC30A2 SLC35C2 SLC39A2 SMIM3 SPAG4 STMN4 STOML3 STX1A STX2 STX4 SUSD3 SYNE4 TFR2 TLCD4 TMED9 TMEM106C TMEM174 TMEM237 TMEM45B TMEM52B TMEM71 TMEM79 TMIE TMPRSS2 TNFSF14 TP53INP1 TRAT1 TRIM59 TYRP1 ZFYVE27	24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2
Entrez ID		26984	6676
HPRD ID		15313	04330
Ensembl ID		ENSG00000121542	ENSG00000061656
Uniprot IDs		Q96IW7	Q9NPE6
PDB IDs
Enriched GO Terms of Interacting Partners?
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