GFER and ASCC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GFER	ASCC2
Description		growth factor, augmenter of liver regeneration	activating signal cointegrator 1 complex subunit 2
Image
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Mitochondrial Intermembrane Space Cytosol	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	Protein Binding Growth Factor Activity Protein-disulfide Reductase Activity Flavin-linked Sulfhydryl Oxidase Activity Flavin Adenine Dinucleotide Binding	Protein Binding Ubiquitin Binding
	Biological Process	Liver Development Signal Transduction	DNA Repair Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		Mitochondrial protein import	ALKBH3 mediated reversal of alkylation damage
Drugs		Flavin adenine dinucleotide
Diseases
GWAS			Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Spleen volume ( 34128465) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		11 interacting genes: ASCC2 BNIPL COPS2 COPS5 METTL9 MTRR NPIPA1 PLEKHF2 SMAD2 TXN YY1	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		2671	84164
HPRD ID		02954	16515
Ensembl ID		ENSG00000127554	ENSG00000100325
Uniprot IDs		P55789	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs		3MBG 3O55 3TK0 3U2L 3U2M 3U5S 4LDK	2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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