GFAP and TBC1D21

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GFAP	TBC1D21
Description		glial fibrillary acidic protein	TBC1 domain family member 21
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Cytosol Intermediate Filament Cell Body Intermediate Filament Cytoskeleton Astrocyte End-foot Cytoplasmic Side Of Lysosomal Membrane	Acrosomal Vesicle Cytoskeleton Extracellular Exosome
	Molecular Function	Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding Kinase Binding Identical Protein Binding	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Intracellular Protein Transport Response To Wounding Gene Expression Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Neuron Projection Development Astrocyte Development Extracellular Matrix Organization Neuron Projection Regeneration Regulation Of Protein-containing Complex Assembly Intermediate Filament Organization Regulation Of Neurotransmitter Uptake Bergmann Glial Cell Differentiation Long-term Synaptic Potentiation D-aspartate Import Across Plasma Membrane Regulation Of Chaperone-mediated Autophagy	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Nuclear signaling by ERBB4 Chaperone Mediated Autophagy
Drugs
Diseases
GWAS		Asthma ( 31619474) Cognitive function ( 25644384) Craniofacial microsomia ( 26853712)	Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		83 interacting genes: ABI2 AKT1 APP AURKB BIRC2 CAMK2A CARD10 CCDC57 CDC37 CDK1 CEP76 CFAP206 CRYAB CT55 CWF19L2 ENKD1 EPM2AIP1 FAM50B FXR1 FXR2 GOLGA2 GRAP2 HGS HOMEZ IKBKG KIAA0408 KRT13 KRT15 KRT19 KRT27 KRT31 KRT39 LENG1 LGALS14 LMO2 MAPK9 MEN1 MOS MYBPHL MYO15B NEFL NEK6 NFKBID NTAQ1 NXF1 PDLIM1 PDLIM7 PDZK1 PIAS2 PIH1D2 POM121 PPP1R16B PPP1R18 PRKACA PRKCA PRKCG PSEN1 PSEN2 RIBC2 ROCK1 RORA S100A1 S100B SH3YL1 SMARCA2 SMARCB1 SRC STAT1 TBC1D21 TBC1D22B TFIP11 TLE5 TP53BP2 TRIM27 TSC1 TUBGCP4 UBASH3A UBE3A VIM YES1 ZC2HC1C ZNF655 ZNF774	29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10
Entrez ID		2670	161514
HPRD ID		00675	15473
Ensembl ID		ENSG00000131095	ENSG00000167139
Uniprot IDs		P14136	Q8IYX1
PDB IDs		6A9P
Enriched GO Terms of Interacting Partners?
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