SEZ6L2 and OASL

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SEZ6L2	OASL
Description		seizure related 6 homolog like 2	2'-5'-oligoadenylate synthetase like
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane
	Molecular Function		2'-5'-oligoadenylate Synthetase Activity DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Thyroid Hormone Receptor Binding
	Biological Process		Response To Virus Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Regulation Of Ribonuclease Activity Interleukin-27-mediated Signaling Pathway Positive Regulation Of RIG-I Signaling Pathway
Pathways			Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Anthropometric traits ( 19260139) Autism spectrum disorder or schizophrenia ( 28540026) Bitter alcoholic beverage consumption ( 31046077) Body fat distribution (arm fat ratio) ( 30664634) Response to taxane treatment (placlitaxel) ( 23006423) Schizophrenia ( 28991256 25056061 29483656) Systemic lupus erythematosus ( 23273568)	Alanine aminotransferase levels ( 33547301) C-reactive protein ( 22939635) C-reactive protein levels ( 24763700 30388399) Cardiovascular disease risk factors ( 21943158) Hematocrit ( 32888494) Hemoglobin ( 32888494) N-glycan levels ( 21908519 21203500) Serum metabolite levels ( 23093944) Type 2 diabetes ( 30054458)
Interacting Genes		7 interacting genes: ETV5 FOXA1 MTDH OASL TK1 TOX3 UNG	3 interacting genes: MBD1 SEZ6L2 THRA
Entrez ID		26470	8638
HPRD ID		06686	04473
Ensembl ID		ENSG00000174938	ENSG00000135114
Uniprot IDs		A0A087WYL5 A0A0A8K8P7 B7Z5L4 Q6UXD5	Q15646
PDB IDs			1WH3 4XQ7
Enriched GO Terms of Interacting Partners?
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