ERAL1 and MIR206

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		ERAL1	MIR206
Description		Era like 12S mitochondrial rRNA chaperone 1	microRNA 206
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol	RISC Complex
	Molecular Function	RNA Binding Protein Binding GTP Binding RRNA Binding Ribosomal Small Subunit Binding	MRNA 3'-UTR Binding Protein Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Ribosomal Small Subunit Assembly	Positive Regulation Of Cell Fate Commitment Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Myotube Differentiation Positive Regulation Of Cholesterol Efflux Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Tumor Necrosis Factor Production Gene Silencing By MiRNA Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Cholesterol Efflux Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Amyloid-beta Formation
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Estimated glomerular filtration rate reduction (30%) ( 30955190) Glycated hemoglobin levels ( 34059833 28898252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 28017375) Mean corpuscular volume ( 29403010) Pulse pressure ( 30224653) Red cell distribution width ( 32888494)
Interacting Genes		47 interacting genes: CEP44 ECT2 MIR1-1 MIR106A MIR106B MIR107 MIR122 MIR138-1 MIR141 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR199A1 MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR29B2 MIR34B MIR451A MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7I SSX2IP TMEM97	78 interacting genes: ADARB1 AIMP1 AQR C1QBP CELF1 CPSF1 CSTF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LCORL LIN28A LIN28B LRPPRC MARS1 MATR3 NOL4L NONO NUDT21 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SF3A3 SF3B1 SF3B2 SF3B3 SFPQ SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX3 ZFR ZNF346
Entrez ID		26284	406989
HPRD ID		08466
Ensembl ID		ENSG00000132591	ENSG00000207604
Uniprot IDs		O75616
PDB IDs
Enriched GO Terms of Interacting Partners?
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