CLEC4E and CXCL9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLEC4E	CXCL9
Description		C-type lectin domain family 4 member E	C-X-C motif chemokine ligand 9
Image			No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Plasma Membrane Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Cell Projection	Extracellular Region Extracellular Space External Side Of Plasma Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Carbohydrate Binding Pattern Recognition Receptor Activity Glycolipid Binding	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Pattern Recognition Receptor Signaling Pathway Innate Immune Response Antifungal Innate Immune Response	Chemotaxis Defense Response Inflammatory Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Regulation Of Cell Population Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion
Pathways		Dectin-2 family Dectin-2 family	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Cholesterol
Diseases
GWAS		Takayasu arteritis ( 25604533)	Blood protein levels ( 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		4 interacting genes: CXCL9 FAM3C FCER1G NKG7	76 interacting genes: AMIGO1 AQP6 ATP1B4 BMF BSCL2 BTNL9 C16orf92 CCL11 CCL13 CCL2 CCL21 CCL26 CCL28 CCL5 CCR3 CD33 CHODL CLDN2 CLDN5 CLDN7 CLEC17A CLEC2D CLEC4E CLEC7A CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL2 CXCR3 DPP4 EPGN EREG FBXO7 FCGR2A FFAR2 FNDC9 FUT7 GJB1 GORAB GPR42 IFNGR2 ITM2C KASH5 KIR2DL3 LDLRAD1 LEUTX LRRC25 LSMEM2 MR1 MTIF3 MUC1 NEMP1 PAX8 PF4 PPBP PTPN5 RHCG SFTPC SLC10A1 SLC39A1 SSMEM1 SUSD3 SYNE4 TM4SF18 TMED5 TMEM106C TMEM234 TMEM237 TMEM31 TMPRSS2 TNFSF14 TNFSF8 TSPAN18 XCL1
Entrez ID		26253	4283
HPRD ID		13075	03416
Ensembl ID		ENSG00000166523	ENSG00000138755
Uniprot IDs		F5H5X7 Q9ULY5	Q07325
PDB IDs		3WH2 3WH3
Enriched GO Terms of Interacting Partners?
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