FBXO2 and PAX4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FBXO2	PAX4
Description		F-box protein 2	paired box 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Membrane SCF Ubiquitin Ligase Complex Dendritic Spine	Chromatin Nucleoplasm
	Molecular Function	Amyloid-beta Binding Ubiquitin-protein Transferase Activity Protein Binding Carbohydrate Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cellular Protein Modification Process Proteolysis Glycoprotein Catabolic Process Negative Regulation Of Cell Population Proliferation Protein Ubiquitination Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination	Regulation Of Transcription By RNA Polymerase II Animal Organ Morphogenesis Cell Differentiation Pancreas Development Anatomical Structure Development
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Fruit consumption ( 32066663) Left-handedness ( 32989287) Metabolite levels ( 23823483) Nonsyndromic cleft palate ( 31609978) Type 2 diabetes ( 32794382 29632382 26818947 32499647 22158537 30718926 23532257) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		17 interacting genes: AHSG BACE1 BRAP ECPAS IGH IL6ST ITGB1 PAX4 PFDN6 SKP1 STUB1 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L3 VSTM1	14 interacting genes: AURKA CABP5 EIF4A3 FBXO2 GMCL1 NAIF1 NECAB1 NFYC NME7 NRXN3 NTM NUTF2 PSMC1 UBL5
Entrez ID		26232	5078
HPRD ID		06171	01333
Ensembl ID		ENSG00000116661	ENSG00000106331
Uniprot IDs		Q9UK22
PDB IDs
Enriched GO Terms of Interacting Partners?
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