NPHP4 and FBXO44

		NPHP4	FBXO44
Description		nephrocystin 4	F-box protein 44
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Ribbon Synapse Ciliary Base Non-motile Cilium Photoreceptor Distal Connecting Cilium	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Signal Transduction Visual Behavior Actin Cytoskeleton Organization Flagellated Sperm Motility Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly Protein Localization To Ciliary Transition Zone	Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process Protein Ubiquitination Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Signaling by Hippo Anchoring of the basal body to the plasma membrane	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Dimensional psychopathology (Positive) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) QT interval ( 19305408) Response to taxane treatment (placlitaxel) ( 23006423)	Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		8 interacting genes: C1orf127 EDIL3 FBXO44 NPHP1 RBP7 RPGRIP1 SCRG1 TMEM201	13 interacting genes: BLOC1S1 BORCS6 BRCA1 C11orf45 HSF2BP ISY1-RAB43 MEOX2 NPHP4 PRDM5 SERTAD3 SKP1 SPG21 UBC
Entrez ID		261734	93611
HPRD ID		06238	16445
Ensembl ID		ENSG00000131697	ENSG00000132879
Uniprot IDs		B3KW36 O75161	A0A024R4F9 A0A024R4J6 B7Z1P2 Q9H4M3
PDB IDs			3WSO 5B4N
Enriched GO Terms of Interacting Partners?
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