SERBP1 and FBXO25

Number of citations of the paper that reports this interaction (PubMedID 23940030)
8

Data Source:
BioGRID (enzymatic study)

		SERBP1	FBXO25
Description		SERPINE1 mRNA binding protein 1	F-box protein 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Ubiquitin Ligase Complex Nucleus Nucleolus Cytoplasm SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding SUMO Binding Ribosome Binding Cadherin Binding	Actin Binding Ubiquitin-protein Transferase Activity
	Biological Process	PML Body Organization Regulation Of Apoptotic Process Regulation Of MRNA Stability	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Carotid plaque burden ( 28282560) Crohn's disease ( 28067908 22412388) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 28067908)	Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Nontraumatic osteonecrosis of the femoral head ( 32701715)
Interacting Genes		24 interacting genes: - APP CHD3 CSNK2A1 DANCR DAXX ESR1 FBXO25 FXYD3 KAT2B OGT PIAS1 PIAS3 PIAS4 PICK1 PRMT8 TDG TERT TOPORS TSPAN15 UBA2 UPF2 VAV2 VIM	83 interacting genes: ANKRD13A APLF AXL BMX BRME1 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DAXX DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GRK2 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ILRUN ING3 IRS1 JHY KDR KRT8 LMCD1 LUC7L MAT2B NKX2-5 NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TBX5 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		26135	26260
HPRD ID		09570	16439
Ensembl ID		ENSG00000142864	ENSG00000147364
Uniprot IDs		Q5VU21 Q63HR1 Q8NC51	A0A024QZ88 Q8TCJ0
PDB IDs		4V6X 6Z6M 6Z6N
Enriched GO Terms of Interacting Partners?
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