PPP1R16B and SSR4

		PPP1R16B	SSR4
Description		protein phosphatase 1 regulatory subunit 16B	signal sequence receptor subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Sec61 Translocon Complex Endomembrane System Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Catalytic Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways			SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		45 interacting genes: ATPAF2 CDCA7L CDK5RAP1 CEP55 CEP70 CRX DVL2 DVL3 FAM83A FAM83D FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MCEE MISP MYL9 NEFL NFX1 PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 SSR4 TACO1 TADA2A TASOR2 TFIP11 TLE5 TTI1 TUFM TXN2 ZNF410 ZNF564	7 interacting genes: HECW1 NLGN3 POMP PPP1R16B PTEN SSR3 TAFAZZIN
Entrez ID		26051	6748
HPRD ID		15168	02101
Ensembl ID		ENSG00000101445	ENSG00000180879
Uniprot IDs		Q96T49	P51571
PDB IDs
Enriched GO Terms of Interacting Partners?
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