ZNF500 and HEXIM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF500	HEXIM2
Description		zinc finger protein 500	HEXIM P-TEFb complex subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding Identical Protein Binding 7SK SnRNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Iron status biomarkers (ferritin levels) ( 33536631) Night sleep phenotypes ( 27126917) Normal facial asymmetry (angle of surface orientation score) ( 30631343)	Asthma ( 31959851 31619474) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Male-pattern baldness ( 28196072) Systolic blood pressure ( 19430483)
Interacting Genes		3 interacting genes: FARS2 HEXIM2 PHF1	49 interacting genes: ADAMTSL4 AHCYL1 AP2M1 CACNB2 CCDC33 CCNT1 CDK9 CFP CTIF DBF4B EGFL7 FAM161A GAS8 GATA1 HEXIM1 HOXA1 HSF2BP IHO1 KPNA3 KPRP KRTAP13-3 LNX1 MEOX2 PICK1 PIM1 PIN1 PRDM14 PSMA1 RNPS1 SAXO1 SDCBP SPRED1 SPRY1 SPRY2 TADA3 TCF12 TERF1 TERF2 TLE5 TNFAIP1 TRIM14 YPEL3 ZNF250 ZNF426 ZNF500 ZNF558 ZNF655 ZNF699 ZNF789
Entrez ID		26048	124790
HPRD ID		18347	08129
Ensembl ID		ENSG00000103199	ENSG00000168517
Uniprot IDs		O60304 Q0VAL1	Q96MH2
PDB IDs
Enriched GO Terms of Interacting Partners?
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