TMEM98 and GJB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM98	GJB1
Description		transmembrane protein 98	gap junction protein beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane Lateral Plasma Membrane
	Molecular Function	Protein Binding	Gap Junction Channel Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Processing Negative Regulation Of Myelination T-helper 1 Cell Differentiation Negative Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Protein Localization To Nucleus	Cell-cell Signaling Nervous System Development Purine Ribonucleotide Transport Gap Junction Assembly Transmembrane Transport Epididymis Development
Pathways			Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases
GWAS		Body mass index ( 28552196) Myopia ( 27182965) Platelet distribution width ( 32888494) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		10 interacting genes: ATP1B3 GJB1 GOLM1 HTR6 MUC1 RABEPK SGTA STOM SUSD3 TNNT1	57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6
Entrez ID		26022	2705
HPRD ID		13171	02367
Ensembl ID		ENSG00000006042	ENSG00000169562
Uniprot IDs		Q9Y2Y6	A0A654ICJ7 P08034
PDB IDs			1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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