CHMP2B and ATP5F1C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP2B	ATP5F1C
Description		charged multivesicular body protein 2B	ATP synthase F1 subunit gamma
Image			No pdb structure
GO Annotations	Cellular Component	ESCRT III Complex Cytoplasm Lysosome Endosome Late Endosome Multivesicular Body Cytosol Plasma Membrane Postsynaptic Density Late Endosome Membrane Extracellular Exosome Glutamatergic Synapse	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Sector F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding Cadherin Binding	RNA Binding Protein Binding ATP Hydrolysis Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Autophagy Nucleus Organization Endosome Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Macroautophagy Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Cognition Multivesicular Body-lysosome Fusion Midbody Abscission Neuron Cellular Homeostasis Regulation Of Modification Of Postsynaptic Structure Regulation Of Postsynapse Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell ESCRT III Complex Disassembly	Oxidative Phosphorylation ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases
GWAS		Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		12 interacting genes: ATP5F1C CENPF CHMP3 DPY30 FBXO7 MALSU1 PHGDH PNMA1 TERF2IP TRAF2 USP54 USP8	30 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CDC42 CHMP2B DPP3 DUX4 EGFR ELOF1 ERCC6 FBXO7 GATA3 GDPD2 ITIH2 MED15 MEOX2 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337
Entrez ID		25978	509
HPRD ID		13174	00156
Ensembl ID		ENSG00000083937	ENSG00000165629
Uniprot IDs		A0A087WW88 B2RE76 Q9UQN3	B4DL14 P36542 Q8TAS0
PDB IDs		2JQK
Enriched GO Terms of Interacting Partners?
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