ZNF521 and EIF1AD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNF521	EIF1AD
Description		zinc finger protein 521	eukaryotic translation initiation factor 1A domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Domain Specific Binding Metal Ion Binding	Translation Initiation Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Commitment	Translational Initiation
Pathways		RUNX2 regulates osteoblast differentiation
Drugs
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Age at first sexual intercourse ( 34211149) Chronotype ( 30696823) Daytime nap ( 33568662) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Height ( 31562340) High density lipoprotein cholesterol levels ( 30498476) Mitochondrial DNA levels ( 25240745) Myeloproliferative neoplasms ( 33057200) Nickel levels ( 26025379) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Systemic juvenile idiopathic arthritis ( 27927641) Takayasu arteritis ( 25604533) Toenail selenium levels ( 25343990) Urgency urinary incontinence ( 25524241) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Serum uric acid levels ( 32271837)
Interacting Genes		8 interacting genes: BRAP EBF1 EIF1AD GATA1 LYST RARS1 SMAD1 SMAD4	34 interacting genes: AP2M1 BEND7 CCDC106 CEP55 CEP76 DPPA2 GAS8 GCSAML GLYR1 GTF2H4 LNX1 MEOX2 MID2 MREG PAX6 PBX4 PICK1 PINX1 RASSF10 RBAK RBM48 SDCBP SDCBP2 STAT1 STX11 TBC1D5 TEPSIN TLE5 TNNI1 ZBTB14 ZBTB8A ZNF280A ZNF521 ZNF558
Entrez ID		25925	84285
HPRD ID		18350	14411
Ensembl ID		ENSG00000198795	ENSG00000175376
Uniprot IDs		J3KTI4 Q8IYZ2 Q96K83	A0A024R5B9 Q8N9N8
PDB IDs			2DGY 6ZXF 6ZXG 6ZXH
Enriched GO Terms of Interacting Partners?
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