ATL3 and POLA2

		ATL3	POLA2
Description		atlastin GTPase 3	DNA polymerase alpha 2, accessory subunit
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Membrane	Nucleoplasm Alpha DNA Polymerase:primase Complex Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding Identical Protein Binding	Molecular_function DNA Binding Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Protein Homooligomerization Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization	DNA Replication DNA Replication, Synthesis Of RNA Primer DNA Replication Initiation
Pathways			Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand Defective pyroptosis
Drugs			Dacarbazine
Diseases
GWAS			Acne (severe) ( 24927181) Hip circumference adjusted for BMI ( 34021172) Serum uric acid levels ( 32514006)
Interacting Genes		4 interacting genes: APP OGT POLA2 TMEM216	41 interacting genes: AGO2 AKTIP APP ARL2 ASCC2 ATL3 ATP5F1C CATSPERZ CPE CRELD1 DCP2 DDX24 DHX34 EIF6 EZH2 FAM219A FGFR3 FRZB HDAC6 HELB HGH1 IGFBP3 KCNE3 KDM2A KLF6 LRPAP1 MFHAS1 NR4A1 PARP1 POLA1 PRIM2 PRPF38A RBM23 SAC3D1 SETDB1 SNU13 STK40 TMEM216 ULK2 XPNPEP1 ZNRD2
Entrez ID		25923	23649
HPRD ID		13170	10160
Ensembl ID		ENSG00000184743	ENSG00000014138
Uniprot IDs		B4DXC4 F5H6I7 Q6DD88	Q14181
PDB IDs		5VGR	2KEB 4E2I 4Y97 5EXR
Enriched GO Terms of Interacting Partners?
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