PRKD2 and RRBP1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
BioGRID (two hybrid)

		PRKD2	RRBP1
Description		protein kinase D2	ribosome binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane	Endoplasmic Reticulum Ribosome Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Kinase C Binding Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity	RNA Binding Signaling Receptor Activity
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Adaptive Immune Response Protein Phosphorylation Cell Adhesion Cell Death Positive Regulation Of Endothelial Cell Migration Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Sphingolipid Biosynthetic Process Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Endothelial Tube Morphogenesis Positive Regulation Of ERK1 And ERK2 Cascade Protein Kinase D Signaling Positive Regulation Of Histone Deacetylase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis	Osteoblast Differentiation Translation Protein Transport
Pathways		Sphingolipid de novo biosynthesis	Signaling by ALK fusions and activated point mutants
Drugs			Radezolid
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Heel bone mineral density ( 30598549) Post bronchodilator FEV1 ( 26634245) Primary sclerosing cholangitis ( 23603763 27992413)	Apolipoprotein A1 levels ( 32203549) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Frontotemporal dementia (age at onset) ( 29724592) Frontotemporal dementia with GRN mutation (age at onset) ( 29724592) HDL cholesterol levels ( 32203549) Height ( 31562340) Iron status biomarkers (total iron binding capacity) ( 33536631) Platelet count ( 32888494) Plateletcrit ( 32888494) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		18 interacting genes: ATP1A3 CASK DST GLRX3 GORASP1 GRIP1 HDAC7 HEY1 IFNAR1 MTF2 PDLIM7 PFDN1 PSG3 RARB RRBP1 RXRA SNRNP70 TGOLN2	4 interacting genes: ATF7IP KIF5B PRKD2 SMAD9
Entrez ID		25865	6238
HPRD ID		09523	11796
Ensembl ID		ENSG00000105287	ENSG00000125844
Uniprot IDs		Q9BZL6	Q9P2E9
PDB IDs		2COA 3BGM 4NNX 4NNY
Enriched GO Terms of Interacting Partners?
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