WHRN and LRRC4C

Number of citations of the paper that reports this interaction (PubMedID 15590698)
91

Data Source:
HPRD (in vitro, two hybrid)

		WHRN	LRRC4C
Description		whirlin	leucine rich repeat containing 4C
Image
GO Annotations	Cellular Component	Photoreceptor Inner Segment Stereocilia Ankle Link Stereocilia Ankle Link Complex Cytoplasm Actin Filament Plasma Membrane Growth Cone Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Ciliary Basal Body Neuronal Cell Body Synapse Periciliary Membrane Compartment USH2 Complex	Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Retina Homeostasis Sensory Perception Of Sound Positive Regulation Of Gene Expression Cerebellar Purkinje Cell Layer Formation Establishment Of Protein Localization Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Sensory Perception Of Light Stimulus Auditory Receptor Cell Stereocilium Organization Inner Ear Receptor Cell Stereocilium Organization Paranodal Junction Maintenance	Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) High myopia ( 31816047) Iris color (L* coordinate) ( 30895295) Mastocytosis (KIT D816V positive) ( 33421400) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Pediatric central nervous system tumors (early onset)(pleiotropy) ( 33226468) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)
Interacting Genes		18 interacting genes: BEND7 BMI1 CASK COL17A1 EFHC1 GOLGA2 GPSM2 HEMGN KEAP1 LRP4 LRRC4C MYO15A MYO7A PXN RPS6KA1 SPC24 TPRN TTF1	29 interacting genes: AGTRAP BDKRB1 BMP10 BRICD5 CLDN19 CLEC1A CLEC4G CMTM5 CREB3L4 DOLK DRAM1 EMP3 GJB2 LEPROTL1 LHFPL5 MIP NTNG1 PGAP2 PLP2 SERTM1 SMIM1 SNAP47 STX5 TRAF6 TWSG1 VEZT VSTM1 WHRN YIPF6
Entrez ID		25861	57689
HPRD ID		09718	12303
Ensembl ID		ENSG00000095397	ENSG00000148948
Uniprot IDs		B9EGE6 Q9P202	Q4JIV9 Q4JIW0 Q9HCJ2
PDB IDs		1UEZ 1UF1 1UFX 6KZ1	3ZYJ
Enriched GO Terms of Interacting Partners?
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