BRMS1 and SUDS3

Number of citations of the paper that reports this interaction (PubMedID 14581478)
77

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		BRMS1	SUDS3
Description		BRMS1 transcriptional repressor and anoikis regulator	SDS3 homolog, SIN3A corepressor complex component
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nucleus Nucleoplasm Cytosol Sin3 Complex Nuclear Body Sin3-type Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding NF-kappaB Binding	Histone Deacetylase Activity Protein Binding Enzyme Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Substantia Nigra Development Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated
Pathways		HDACs deacetylate histones Potential therapeutics for SARS	HDACs deacetylate histones NoRC negatively regulates rRNA expression Ub-specific processing proteases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756)	Glucose homeostasis traits ( 25524916) Hemostatic factors and hematological phenotypes ( 22443383) Hippocampal sclerosis ( 25188341) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
Interacting Genes		49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1	9 interacting genes: BRMS1 COL6A3 CSNK2A1 DYNLL1 GOLGA2 HDAC1 LDOC1 PTEN SRPK1
Entrez ID		25855	64426
HPRD ID		05879	12196
Ensembl ID		ENSG00000174744	ENSG00000111707
Uniprot IDs		G5E9I4 Q9HCU9	Q9H7L9
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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