SPDEF and SNX20

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SPDEF	SNX20
Description		SAM pointed domain containing ETS transcription factor	sorting nexin 20
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Plasma Membrane Early Endosome Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Negative Regulation Of Cell Fate Commitment Positive Regulation Of Cell Fate Commitment Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Lung Goblet Cell Differentiation Intestinal Epithelial Cell Development	Protein Transport
Pathways
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronic lymphocytic leukemia (time to first treatment) ( 33510140) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 27569725) Refractive error ( 32231278) Weight ( 28552196)	Asthma (childhood onset) ( 31036433) Crohn's disease ( 28008999 28067908 22412388) Inflammatory bowel disease ( 28008999 28067908)
Interacting Genes		13 interacting genes: AR CEP57 COX5A ENKD1 ESR1 FAM161B NKX3-1 PCGF2 PSMA1 SNX20 SRPK2 STK11 TTC23	9 interacting genes: ALAS1 FAM9B GMCL1 KLHL12 MAGEA11 NFATC3 SPDEF TACC3 TFIP11
Entrez ID		25803	124460
HPRD ID		12176	15401
Ensembl ID		ENSG00000124664	ENSG00000167208
Uniprot IDs		O95238	Q7Z614
PDB IDs		1YO5 2DKX
Enriched GO Terms of Interacting Partners?
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