RNF144B and CHCHD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RNF144B	CHCHD2
Description		ring finger protein 144B	coiled-coil-helix-coiled-coil-helix domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol Integral Component Of Membrane Mitochondrial Membrane	Nucleus Mitochondrion Mitochondrial Intermembrane Space
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Sequence-specific DNA Binding DNA-binding Transcription Factor Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process	Mitochondrion Organization Cellular Response To Oxidative Stress Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Hypoxia Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Mitochondrial protein import
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at voice drop ( 27182965) Caudal middle frontal gyrus volume ( 31530798) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Endometriosis ( 23472165) Facial morphology ( 31763980) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (Dorea) ( 33208821) Pulse pressure ( 30224653) Thiopurine S-methyltransferase activity ( 27770449) Triglyceride levels ( 32203549)	Macular telangiectasia type 2 ( 33654266) Metabolite levels ( 23823483 31628463) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259)
Interacting Genes		29 interacting genes: ANKS1A CDKN1A CHCHD2 CREB5 DTNBP1 FOXH1 IL16 OTX1 PAN2 PAX5 PRKAB2 PROP1 PRR35 RIPPLY1 SGTA SGTB TRAF4 UBC UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z UBQLN1 USP15 USP2 VENTX ZIC1	31 interacting genes: ADAMTSL4 ADRA2C CHCHD10 CRYBA1 CTAG1A CTAG1B CYSRT1 EHMT2 FBXO7 GOLGA2 IKZF3 INCA1 KRT31 KRT40 LHX4 MIF4GD OIP5 P4HB PBX4 PLEKHF2 POLDIP2 REL RNF144B TCF4 TRAF2 TREX1 TRIM42 TRIM54 TSC1 USP54 ZMYND12
Entrez ID		255488	51142
HPRD ID		17126	09879
Ensembl ID		ENSG00000137393	ENSG00000106153
Uniprot IDs		Q7Z419	Q9Y6H1
PDB IDs
Enriched GO Terms of Interacting Partners?
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