GABPA and ATF1

Number of citations of the paper that reports this interaction (PubMedID 10585419)
7

Data Source:
HPRD (in vitro)

		GABPA	ATF1
Description		GA binding protein transcription factor subunit alpha	activating transcription factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex ATF4-CREB1 Transcription Factor Complex ATF1-ATF4 Transcription Factor Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein-containing Complex Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dopamine	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Response To Organic Cyclic Compound Response To Cobalt Ion Cellular Protein-containing Complex Assembly Positive Regulation Of DNA Replication Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Transcriptional activation of mitochondrial biogenesis	CREB phosphorylation NGF-stimulated transcription NGF-stimulated transcription
Drugs			Pseudoephedrine
Diseases
GWAS		Glaucoma (primary open-angle) ( 33627673) Gout (normal type) ( 32238385) Nicotine dependence symptom count ( 25555482)	Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 32203549) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Colorectal cancer ( 25990418 20972440 24737748) Colorectal cancer or advanced adenoma ( 30510241) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163) HDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Male-pattern baldness ( 27182965) Mean arterial pressure ( 27618448) Multiple sclerosis ( 31604244) Spleen volume ( 34128465) Sudden cardiac arrest ( 21658281) Systolic blood pressure ( 30578418)
Interacting Genes		15 interacting genes: APP ATF1 CREBBP EP300 GABPB1 GABPB2 HCFC1 MED1 OGT PINX1 SP1 SP3 STK16 TMPRSS15 ZC2HC1B	23 interacting genes: BRCA1 CAMK1 CAMK2A CAMK2G CREB1 CREBBP CREM CSNK2A1 CSNK2A2 CSNK2B DNMT3L EDF1 GABPA GABPB1 HNF1B JUN MAPKAPK2 MAPKAPK3 PRKACA RPS6KA4 RPS6KA5 SPI1 SRA1
Entrez ID		2551	466
HPRD ID		11793	00440
Ensembl ID		ENSG00000154727	ENSG00000123268
Uniprot IDs		A8IE48 Q06546 Q8IYS3	P18846
PDB IDs
Enriched GO Terms of Interacting Partners?
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