Description |
GRB2 associated binding protein 1 |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Staurosporine
- Myricetin
- LY-294002
- Quercetin
- 5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE
- XL765
- TG100-115
- 2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE
- N-(5-{4-Chloro-3-[(2-hydroxyethyl)sulfamoyl]phenyl}-4-methyl-1,3-thiazol-2-yl)acetamide
- 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one
- 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL
- (5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE
- Wortmannin
- 1-methyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Duvelisib
- Fostamatinib
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Diseases |
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GWAS |
- Asthma ( 21804548)
- Diastolic blood pressure ( 27841878)
- Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
- Estimated glomerular filtration rate in non-diabetics ( 31451708)
- Height ( 31562340)
- Malaria ( 31844061)
- Systolic blood pressure ( 27841878)
- Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
- Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
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Interacting Genes |
71 interacting genes:
ARHGAP32
BCAR3
BLK
BLNK
BTK
C1QBP
CRK
CRKL
EGFR
EPOR
ERBB2
FCGR2B
FES
FRS2
GAB2
GRAP2
GRB2
GTF2A1L
HCK
HSH2D
INPP5D
INPPL1
INSR
ITK
JAK1
LAT2
MAP3K3
MAPK1
MAPK3
MAPK4
MARK2
MET
MST1R
NCK1
NCK2
PDGFRB
PIK3CG
PIK3R1
PIK3R2
PIK3R3
PLCG1
PLCG2
PTK6
PTPN11
PTPN18
RASA1
RET
SH2D1B
SH2D2A
SH2D3A
SHC1
SHC3
SLA
SLA2
SOCS3
SOCS6
SOS1
SRC
STAP1
SUPT6H
SYK
SYP
TEC
TNS1
TNS3
TNS4
TRIM15
VAV1
VAV2
VAV3
YES1
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22 interacting genes:
CD28
EPHA8
GAB1
GRB2
GRK2
GSN
HRAS
IL6ST
KIT
KRAS
LYN
NOTCH1
NRAS
PIK3CD
PIK3R5
PIK3R6
PTPN11
SEC14L2
SET
SMPD2
TPM2
ZNF282
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Entrez ID |
2549 |
5294 |
HPRD ID |
05116 |
03135 |
Ensembl ID |
ENSG00000109458
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ENSG00000105851
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Uniprot IDs |
Q13480
Q9HA84
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A0A024R720
A8K9G9
P48736
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PDB IDs |
4QSY
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1E8Y
1E8Z
1HE8
2A4Z
2A5U
2CHW
2CHX
2CHZ
2V4L
3APC
3APD
3APF
3CSF
3CST
3DBS
3DPD
3ENE
3IBE
3L08
3L13
3L16
3L17
3L54
3LJ3
3MJW
3ML8
3ML9
3NZS
3NZU
3OAW
3P2B
3PRE
3PRZ
3PS6
3QAQ
3QAR
3QJZ
3QK0
3R7Q
3R7R
3S2A
3SD5
3T8M
3TJP
3TL5
3ZVV
3ZW3
4ANU
4ANV
4ANW
4ANX
4AOF
4DK5
4EZJ
4EZK
4EZL
4F1S
4FA6
4FAD
4FHJ
4FHK
4FJY
4FJZ
4FLH
4FUL
4G11
4GB9
4HLE
4HVB
4J6I
4KZ0
4KZC
4PS3
4PS7
4PS8
4URK
4WWN
4WWO
4WWP
4XX5
4XZ4
5EDS
5G2N
5G55
5JHA
5JHB
5KAE
5OQ4
5T23
6AUD
6C1S
6FH5
6GQ7
6T3B
6T3C
6XRL
6XRM
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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