XRCC6 and HERPUD1

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 136
  • Data Source:
  • BioGRID (two hybrid)

XRCC6

HERPUD1

Description X-ray repair cross complementing 6 homocysteine inducible ER protein with ubiquitin like domain 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aspartate aminotransferase levels ( 33547301)
  • Cardiovascular risk factors ( 20838585)
  • Coronary artery disease ( 29212778)
  • Diisocyanate-induced asthma ( 25918132)
  • HDL cholesterol ( 20031564 23505323 24886709)
  • HDL Cholesterol in HIV-infection ( 25884002)
  • HDL cholesterol levels ( 26763881 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • High density lipoprotein cholesterol levels ( 29403010 33339817)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hypo-HDL-cholesterolemia ( 31087446)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Low HDL-cholesterol levels ( 31910446)
  • Metabolic syndrome ( 20694148)
  • Metabolite levels ( 23823483)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 29403010 33339817)
  • Triglyceride levels ( 29403010 33339817)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes 135 interacting genes: ABCD4 ABL1 ACD ADCY7 APEX1 AR ARAP1 ATP23 ATP6V1E1 BARD1 BAZ1A BTG1 CAPN11 CBX5 CCNA1 CCT3 CD40 CDCA5 CDK2 CDKN1A CEBPA CENPU CHAF1A CHEK1 CLTC CLU CMTM6 COIL COPB1 CREBBP CSNK2A1 CTBP2 DLX2 DNTT DUX4 DYSF EFNA1 EGFR EID1 ELF3 EP300 EPS8 ETS1 FMNL1 GAL3ST4 GSE1 GZMA GZMB HERPUD1 HMGA2 HOXB7 HOXC4 HOXD4 HSF1 HTT ILVBL JPT2 KAT2A KAT2B KIAA0408 LIG3 MAP2K5 MAP4K2 MAPK8 MRE11 MSX2 NAA15 NCF4 NCL NCOA6 NIT1 NOTCH1 OGT PAEP PAFAH1B3 PARP1 PCNA PDK1 PDPK1 PDX1 PECAM1 PGAM1 PGR PIN1 PLGRKT PNRC2 POR POU2F1 POU2F2 PRKDC PRPF40A PTEN PTTG1 QRSL1 RASA1 RBBP4 RGS2 RNF126 RNF146 RPLP1 RPS10 RRAS2 RUNX2 SDHC SELENOF SERPINA2 SERPINB9 SET SGO1 SIRT3 SKIL SMAD3 SMAD7 SNTA1 SNU13 SPARC SUMO2 TAC1 TADA3 TBCD TCF4 TERF2 TERT TOP1 TP53 UBC USP14 VAV1 VBP1 WBP4 WRN XRCC5 YWHAZ ZBTB7A ZNF512B 20 interacting genes: AMFR APP ARHGDIA C5AR2 CCR2 CD3D CD58 CHRM2 EWSR1 F2RL1 IMPA2 PSEN1 RPA2 SH3RF1 STARD9 TOLLIP UBQLN2 USP7 VCP XRCC6
Entrez ID 2547 9709
HPRD ID 01071 07456
Ensembl ID ENSG00000196419 ENSG00000051108
Uniprot IDs A0A024R1N4 B1AHC9 B4DE32 B4E356 P12956 A4UAE9 Q15011 Q53FP9
PDB IDs 1JEQ 1JEY 1JJR 3RZX 5Y3R 6ERF 6ERG 6ERH 6ZHA 6ZHE 7AXZ 7K0Y 7K1J 7K1K 7K1N 1WGD
Enriched GO Terms of Interacting Partners?
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