STH and CSTF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STH	CSTF2
Description		saitohin	cleavage stimulation factor subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Nuclear Body Cleavage Body
	Molecular Function	Protein Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Positive Regulation Of MRNA Splicing, Via Spliceosome	MRNA Polyadenylation Pre-mRNA Cleavage Required For Polyadenylation Cellular Response To Nerve Growth Factor Stimulus
Pathways			tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol use disorder (total score) ( 30336701) Brain morphology (MOSTest) ( 32665545) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Idiopathic pulmonary fibrosis ( 24429156) Intracranial volume ( 22504418) Male-pattern baldness ( 28196072) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Parkinson's disease ( 28892059 22438815) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Sleep duration ( 30531941) Subcortical brain region volumes ( 25607358)
Interacting Genes		16 interacting genes: CSTF2 CSTF2T FRS3 MKRN3 NTAQ1 PEF1 PITX1 POGZ PRDX6 SMARCD1 SNRPC SOHLH1 SUOX TFG TLX3 VPS37C	48 interacting genes: ABHD11 AKAP8L ANKRD10 APP ATP23 BAG6 CDSN CEACAM6 CEP126 CHD3 CNOT2 CSTF3 CTBP2 DDX1 ECH1 EEF1G ELP1 ERG28 FAM168B FEZ1 HDHD3 HGS IMMT INCA1 KAT5 METTL15 METTL27 MIR19A MIR92A2 POLR2A POU6F2 PPP1R32 PRDM6 RFX6 SPAG8 SS18L1 STH SUB1 SYMPK TFG TLE3 TLE5 TSC1 UBQLN1 UBQLN4 UFSP1 USP54 ZNF341
Entrez ID		246744	1478
HPRD ID		06142	02652
Ensembl ID		ENSG00000256762	ENSG00000101811
Uniprot IDs		Q8IWL8	B3V096 B4DUD5 E7EWR4 P33240
PDB IDs			1P1T 2J8P 6Q2I 6TZE
Enriched GO Terms of Interacting Partners?
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