PRPF6 and CD2BP2

Number of citations of the paper that reports this interaction (PubMedID 27173435)
78

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid)

		PRPF6	CD2BP2
Description		pre-mRNA processing factor 6	CD2 cytoplasmic tail binding protein 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Fibrillar Center Nucleus Nucleoplasm U5 SnRNP Cytoplasm Cytosol Nuclear Speck U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Transcription Coactivator Activity RNA Binding Protein Binding Identical Protein Binding Ribonucleoprotein Complex Binding Androgen Receptor Binding	Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II	Spliceosomal Tri-snRNP Complex Assembly
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732) Refractive error ( 32231278)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: AR ARAF CD2BP2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 SUMO2 TIMM44 TXNL4B YWHAB	15 interacting genes: ACAD11 AKNA CD2 CHRM3 CSNK2A1 LRRK1 OGT PRPF6 PSMF1 SMU1 SNRPB TRAPPC6A TXNL4A WBP11 ZNHIT2
Entrez ID		24148	10421
HPRD ID		10729	05127
Ensembl ID		ENSG00000101161	ENSG00000169217
Uniprot IDs		O94906	A0A024QZC1 O95400
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	1GYF 1L2Z 1SYX 4BWS
Enriched GO Terms of Interacting Partners?
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