EML2 and EIF3F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EML2	EIF3F
Description		EMAP like 2	eukaryotic translation initiation factor 3 subunit F
Image
GO Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Associated Complex Mitotic Spindle	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Signaling Receptor Binding Protein Binding Microtubule Binding Protein C-terminus Binding Tubulin Binding	Translation Initiation Factor Activity Thiol-dependent Deubiquitinase Protein Binding Metallopeptidase Activity Translation Initiation Factor Binding Identical Protein Binding Isopeptidase Activity Deubiquitinase Activity
	Biological Process	Microtubule Cytoskeleton Organization Visual Perception Sensory Perception Of Sound Regulation Of Microtubule Nucleation Negative Regulation Of Microtubule Polymerization	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Protein Deubiquitination IRES-dependent Viral Translational Initiation
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs			Quercetin
Diseases
GWAS		Fruit consumption ( 32066663) Hemoglobin A1c levels ( 29403010) Subcutaneous adipose tissue ( 22589738) Type 2 diabetes ( 32499647)	Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221) Malaria ( 31844061) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		13 interacting genes: BPIFA1 EIF3F EXD1 IFI35 IFT88 KLHDC2 PLEKHF2 PTTG2 REL RFC5 SNX32 SPANXA1 SPANXA2	45 interacting genes: AGR2 APP ATXN1 C1orf216 C6orf201 CCDC120 CCDC196 CDC42 CDK11A CDK11B CDK19 CDSN COL1A2 DKC1 EEF1A1 EIF3M EML2 ERCC6 FBXO32 HAX1 HGS HNRNPK HTR2A MCPH1 MKRN2 MSH4 MTOR MYDGF MYOZ1 NUP54 OGT PBX4 PKN1 POGZ POU6F2 PTN RABIF RIN1 RPS6KB1 RTP5 SHBG SMAD9 SUOX TIMM10B WASHC1
Entrez ID		24139	8665
HPRD ID		16860	04887
Ensembl ID		ENSG00000125746	ENSG00000175390
Uniprot IDs		O95834	O00303
PDB IDs		4CGB	3J8B 3J8C 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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