FLRT3 and UNC5B

Number of citations of the paper that reports this interaction (PubMedID 21673655)
58

Data Source:
BioGRID (pull down, pull down)

		FLRT3	UNC5B
Description		fibronectin leucine rich transmembrane protein 3	unc-5 netrin receptor B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion Cell Junction Extracellular Matrix Growth Cone Membrane Axon Terminus Axonal Growth Cone Synaptic Membrane Glutamatergic Synapse Integral Component Of Postsynaptic Membrane	Plasma Membrane Integral Component Of Membrane Membrane Raft
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Protein-macromolecule Adaptor Activity Protein Homodimerization Activity Chemorepellent Activity	Netrin Receptor Activity Protein Binding
	Biological Process	Proepicardium Cell Migration Involved In Pericardium Morphogenesis Axon Guidance Synapse Assembly Heart Development Fibroblast Growth Factor Receptor Signaling Pathway Neuron Projection Development Embryonic Morphogenesis Response To Axon Injury Negative Chemotaxis Positive Regulation Of Synapse Assembly Head Development Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Synaptic Membrane Adhesion Neuron Projection Extension	Angiogenesis Apoptotic Process Axon Guidance Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Signaling by ROBO receptors Downstream signaling of activated FGFR1	Netrin-1 signaling Netrin mediated repulsion signals Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS		Bipolar disorder ( 33169155) Blood protein levels ( 30072576 29875488) Mood disorder in prion disease ( 25897833)	Attention deficit hyperactivity disorder ( 18839057) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 33772158) Diisocyanate-induced asthma ( 25918132) Problematic alcohol use ( 32451486) Vitiligo ( 22951725)
Interacting Genes		3 interacting genes: FGFR1 IRF4 UNC5B	5 interacting genes: DAPK1 FLRT3 OIT3 PPP2R1B TREM2
Entrez ID		23767	219699
HPRD ID		05313	08487
Ensembl ID		ENSG00000125848	ENSG00000107731
Uniprot IDs		Q9NZU0	Q8IZJ1
PDB IDs		5CMN 5CMP 6JBU
Enriched GO Terms of Interacting Partners?
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