SLC7A11 and SLC3A2

Number of citations of the paper that reports this interaction (PubMedID 12235164)
158

Data Source:
HPRD (in vivo)

		SLC7A11	SLC3A2
Description		solute carrier family 7 member 11	solute carrier family 3 member 2
Image		No pdb structure
GO Annotations	Cellular Component	Rough Endoplasmic Reticulum Cytoskeleton Plasma Membrane Cell Surface Integral Component Of Membrane Brush Border Membrane Apical Part Of Cell Astrocyte Projection	Nucleoplasm Lysosomal Membrane Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Melanosome Apical Pole Of Neuron Synapse Extracellular Exosome Amino Acid Transport Complex
	Molecular Function	Protein Binding L-amino Acid Transmembrane Transporter Activity Cystine:glutamate Antiporter Activity	RNA Binding Double-stranded RNA Binding Catalytic Activity Calcium:sodium Antiporter Activity Protein Binding Aromatic Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Cadherin Binding
	Biological Process	Amino Acid Transmembrane Transport Glutathione Metabolic Process Visual Learning Response To Toxic Substance Response To Organic Cyclic Compound Ventricular System Development Striatum Development Adult Behavior Regulation Of Neutrophil Apoptotic Process Cellular Response To Oxidative Stress Glutathione Transmembrane Transport Response To Nicotine Regulation Of Cell Population Proliferation Regulation Of Melanin Biosynthetic Process Lung Alveolus Development Modulation Of Chemical Synaptic Transmission Regulation Of Synapse Organization Regulation Of Protein Transport Response To Redox State Limb Development Lens Fiber Cell Differentiation Platelet Aggregation Glutamate Homeostasis L-glutamate Import Across Plasma Membrane Dipeptide Import Across Plasma Membrane Regulation Of Cysteine Metabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Glutathione Biosynthetic Process Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Glutamate Metabolic Process	Carbohydrate Metabolic Process Calcium Ion Transport Amino Acid Transport Leucine Transport Phenylalanine Transport Tryptophan Transport Sodium Ion Transmembrane Transport Response To Exogenous DsRNA Viral Entry Into Host Cell Leucine Import Across Plasma Membrane L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways		Basigin interactions Amino acid transport across the plasma membrane	Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI) Tryptophan catabolism
Drugs		Cystine Glutamic acid Riluzole Sulfasalazine Acetylcysteine Thimerosal
Diseases
GWAS		Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mood instability ( 31168069) Neurociticism ( 29500382) Sleep duration (> 10 hours) ( 33075057)	Iron status biomarkers (transferrin saturation) ( 28334935) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: BAAT KRTAP1-1 KRTAP1-3 OTUB1 SLC3A2 TERT	17 interacting genes: CCR4 EBP EGFR GPR37 HNRNPD ICAM1 ITGB1 MTNR1B NPSR1 RELA SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 TLCD3A VHL
Entrez ID		23657	6520
HPRD ID		09720	01148
Ensembl ID		ENSG00000151012	ENSG00000168003
Uniprot IDs		Q9UPY5	J3KPF3 P08195
PDB IDs			2DH2 2DH3 6IRS 6IRT 6JMQ 6JMR 6S8V 7CCS 7CMH 7CMI
Enriched GO Terms of Interacting Partners?
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