LDOC1 and INPP1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
172

Data Source:
BioGRID (two hybrid, two hybrid)

		LDOC1	INPP1
Description		LDOC1 regulator of NFKB signaling	inositol polyphosphate-1-phosphatase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Cytosol
	Molecular Function	Protein Binding	Inositol-1,4-bisphosphate 1-phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Phosphate-containing Compound Metabolic Process Signal Transduction Phosphatidylinositol Phosphate Biosynthetic Process Inositol Phosphate Dephosphorylation
Pathways			Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases
GWAS			Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Lung cancer (SNP x SNP interaction) ( 24325914) Machado-Joseph disease (age at onset) ( 32205469)
Interacting Genes		107 interacting genes: AATF ABLIM1 AEBP2 AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL C1orf109 CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PEG10 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	11 interacting genes: BBLN BRCA1 DYNLL1 LDOC1 LIG1 MEOX2 NDC80 NECAB2 NR1D1 SYCE3 USHBP1
Entrez ID		23641	3628
HPRD ID		02322	00923
Ensembl ID		ENSG00000182195	ENSG00000151689
Uniprot IDs		O95751	P49441 Q6IBG4
PDB IDs
Enriched GO Terms of Interacting Partners?
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