DNAAF11 and LSM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DNAAF11	LSM2
Description		dynein axonemal assembly factor 11	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Cilium Motile Cilium Apical Cytoplasm Dynein Axonemal Particle	P-body Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex
	Molecular Function	Molecular_function Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding Small GTPase Binding
	Biological Process	Cilium Movement Epithelial Cilium Movement Involved In Extracellular Fluid Movement Male Gonad Development Flagellated Sperm Motility Outer Dynein Arm Assembly Inner Dynein Arm Assembly Regulation Of Protein Binding Motile Cilium Assembly Establishment Of Localization In Cell Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Reproductive System Development Protein Localization To Cilium Axonemal Dynein Complex Assembly Cerebrospinal Fluid Circulation Protein Localization To Motile Cilium	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome MRNA Catabolic Process
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Rosacea symptom severity ( 29771307) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: DDX6 LRCH3 LSM2 MEOX2 PLEKHF2 PODN SSX7 ST3GAL1 TERF1 TSC22D2 TTC23L	37 interacting genes: BANP CBX8 CRMP1 DNAAF11 DNAJA1 ERG28 EXOSC10 GBP2 KRT13 LGALS7 LGALS7B LNX1 LSM1 LSM12 LSM3 LSM5 LSM6 LSM7 LSM8 LZTS1 MAGEA3 MAGEA6 MEOX2 PATL1 PNMA1 RALA REL RSRC1 SF3B2 SMN1 SNRPD2 SNRPE TEX11 TLE5 TRIM54 ZBTB16 ZNF408
Entrez ID		23639	57819
HPRD ID		10286	06282
Ensembl ID		ENSG00000129295	ENSG00000204392
Uniprot IDs		Q86X45	Q9Y333
PDB IDs			3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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