TSPAN15 and GYPC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSPAN15	GYPC
Description		tetraspanin 15	glycophorin C (Gerbich blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Nuclear Body Cell Junction Late Endosome Membrane Intracellular Membrane-bounded Organelle Tetraspanin-enriched Microdomain	Plasma Membrane Integral Component Of Plasma Membrane Membrane Cortical Cytoskeleton
	Molecular Function	Protein Binding Enzyme Binding	Protein Binding
	Biological Process	Regulation Of Notch Signaling Pathway Negative Regulation Of Notch Signaling Pathway Protein Maturation Protein Localization To Plasma Membrane
Pathways		Amyloid fiber formation	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Response to taxane treatment (placlitaxel) ( 23006423) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Thrombosis ( 26908601) Type 2 diabetes ( 32499647) Venous thromboembolism ( 25772935 28373160 31420334 31676865)	Atrial fibrillation ( 30061737 29892015) Diastolic blood pressure ( 30224653) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Initial pursuit acceleration ( 29064472) Intelligence ( 22449649) Metabolite levels ( 23823483) Pelvic organ prolapse (moderate/severe) ( 26545240) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 31217584) Tea consumption ( 31046077)
Interacting Genes		14 interacting genes: ADAMDEC1 BTRC CHI3L1 GYPC KLRC3 RGS2 RUFY2 SERBP1 SETDB1 SLC25A16 STRIT1 SYNE4 TCHP TSPO	13 interacting genes: ABHD16A AQP6 EPB41 GPR42 MPP1 PDIA3 PLPPR2 RHBDD1 SHISAL1 SLC10A6 TMEM14B TMEM88 TSPAN15
Entrez ID		23555	2995
HPRD ID		15511	00193
Ensembl ID		ENSG00000099282	ENSG00000136732
Uniprot IDs		O95858	P04921
PDB IDs			2EJY
Enriched GO Terms of Interacting Partners?
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