PIK3R5 and SDHB

Number of citations of the paper that reports this interaction (PubMedID 18624398)
18

Data Source:
BioGRID (two hybrid)

		PIK3R5	SDHB
Description		phosphoinositide-3-kinase regulatory subunit 5	succinate dehydrogenase complex iron sulfur subunit B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Phosphatidylinositol 3-kinase Complex Phosphatidylinositol 3-kinase Complex, Class IB Membrane Centriolar Satellite	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Plasma Membrane Mitochondrial Membrane
	Molecular Function	G-protein Beta/gamma-subunit Complex Binding 1-phosphatidylinositol-3-kinase Regulator Activity	Protein Binding Succinate Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding Ubiquinone Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Phosphatidylinositol 3-kinase Signaling Positive Regulation Of MAP Kinase Activity Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Protein Kinase B Signaling	Tricarboxylic Acid Cycle Succinate Metabolic Process Aerobic Respiration Respiratory Electron Transport Chain
Pathways		GPVI-mediated activation cascade Synthesis of PIPs at the plasma membrane G beta:gamma signalling through PI3Kgamma Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Respiratory electron transport Citric acid cycle (TCA cycle)
Drugs			2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Atypical femoral fracture in phosphonate treatment ( 31006051) Autoimmune thyroid disease ( 32581359) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Monocyte percentage of white cells ( 32888494)	Body shape index ( 34021172) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 20189936) Hip circumference adjusted for BMI ( 34021172) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: APP PIK3CG SDHB SNX9	16 interacting genes: ABCA1 CA6 CARTPT FLOT1 GEM MFAP2 MSRA PIK3R5 RAP1GAP RPL11 SLC45A1 SLC9A1 SPRY2 STMN1 TARBP1 XRN1
Entrez ID		23533	6390
HPRD ID		11433	01707
Ensembl ID		ENSG00000141506	ENSG00000117118
Uniprot IDs		J3KSW1 L7RT34 Q8WYR1	P21912
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?