ARHGAP45 and RPL36

		ARHGAP45	RPL36
Description		Rho GTPase activating protein 45	ribosomal protein L36
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GO Annotations	Cellular Component	Extracellular Region Cytosol Membrane Ruffle Membrane Secretory Granule Lumen Azurophil Granule Lumen	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Polysomal Ribosome
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Intracellular Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity	Cytoplasmic Translation Translation
Pathways		Neutrophil degranulation RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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Diseases
GWAS
Interacting Genes		10 interacting genes: BICD2 GMIP GOLGA2 HSF2BP PIBF1 PPP1R13B RINT1 RPL36 TRIM50 ZUP1	12 interacting genes: APP APPL2 ARHGAP45 DAZAP1 DUX4 KLHL4 NR2C2 PIP5K1C PTEN RPL18A SHC2 TESC
Entrez ID		23526	25873
HPRD ID		03097	10201
Ensembl ID		ENSG00000180448	ENSG00000130255
Uniprot IDs		B3KVA9 B3KXW7 F5H1R4 K7ES92 K7ES98 Q8IYN3 Q92619	Q9Y3U8
PDB IDs		3D25 3FT3	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP
Enriched GO Terms of Interacting Partners?
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