SF3B3 and PHF5A

Number of citations of the paper that reports this interaction (PubMedID 27720643)
84

Data Source:
BioGRID (pull down, affinity chromatography technology)

		SF3B3	PHF5A
Description		splicing factor 3b subunit 3	PHD finger protein 5A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm U2 SnRNP U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm U2 SnRNP U12-type Spliceosomal Complex Nuclear Matrix Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	Protein Binding U2 SnRNA Binding Protein-containing Complex Binding	DNA Binding RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process	MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription, DNA-templated Stem Cell Differentiation
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway
Drugs		Quercetin
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Malaria ( 31844061)	Asthma ( 30929738 32296059) Asthma (childhood onset) ( 30929738) Chronotype ( 30696823) Experiencing mood swings ( 29500382) Feeling tense ( 29500382) Lamb consumption ( 32066663) Meat-related diet ( 32066663) Neuroticism ( 29255261) PR interval ( 32439900) Refractive error ( 32231278)
Interacting Genes		107 interacting genes: APBB1 EFTUD2 EPS8 ERCC6 ERG HCK HGS HSPB1 KLF10 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MPP3 NAGK NOL12 NUTF2 OSGEP PHF5A PLA2G15 PPIL1 PRKN PRPF40A RAD9A RBM6 RUFY2 SF3B1 SF3B6 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 U2AF2 WBP4 WWOX YWHAG ZNF579	10 interacting genes: AP1B1 CENPM FOXB1 PRPF31 SF3B1 SF3B3 SF3B6 SUMO2 U2AF2 ZDHHC17
Entrez ID		23450	84844
HPRD ID		12027	15126
Ensembl ID		ENSG00000189091	ENSG00000100410
Uniprot IDs		A8K6V3 Q15393	A0A024R1U2 Q7RTV0
PDB IDs		5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9 6Y50 6Y5Q 7ABG 7ABH 7ABI	5IFE 5O9Z 5SYB 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9 6Y50 6Y5Q 7ABG 7ABH 7ABI
Enriched GO Terms of Interacting Partners?
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