RYBP and GABPB1

Number of citations of the paper that reports this interaction (PubMedID 11953439)
16

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		RYBP	GABPB1
Description		RING1 and YY1 binding protein	GA binding protein transcription factor subunit beta 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Apoptotic Process Multicellular Organism Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Histone H2A Monoubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated	Mitochondrion Organization Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Body size at age 10 ( 32376654) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 28552196 20881960 25282103 25429064 23563607 31562340) Hip circumference adjusted for BMI ( 34021172) Medication use (beta blocking agents) ( 31015401) Metabolite levels ( 23823483) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Resting-state electroencephalogram vigilance ( 29703947) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)	Superior frontal gyrus volume ( 31530798)
Interacting Genes		34 interacting genes: ABL1 BANP CASP10 CASP8 CBX2 CRK E2F2 E2F3 E2F4 E2F6 EAF1 FADD FANK1 FHL3 GABPB1 GABPB2 HSPB1 MAPK8IP2 MDM2 NMI NOS1AP PSMB1 PTEN RBBP4 RING1 RNF2 RNF8 SOCS2 UBC UBE3A XAGE1A XAGE1B YY1 ZFP42	29 interacting genes: ADGRB2 ATF1 BAIAP2L2 CIC FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 MED20 POGZ RBM11 RSPH14 RYBP SLC27A2 SNRPA SNRPB2 SNW1 TDRD7 TRAF2 TRIM55 TRIM63 USO1 YAF2 ZDHHC17
Entrez ID		23429	2553
HPRD ID		09607	15975
Ensembl ID		ENSG00000163602	ENSG00000104064
Uniprot IDs		Q8N488	A0A024R5R5 A0A024R5X6 Q06547
PDB IDs		3IXS
Enriched GO Terms of Interacting Partners?
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