PIP5K1C and RPL36

		PIP5K1C	RPL36
Description		phosphatidylinositol-4-phosphate 5-kinase type 1 gamma	ribosomal protein L36
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GO Annotations	Cellular Component	Phagocytic Cup Uropod Nucleoplasm Cytosol Adherens Junction Focal Adhesion Endosome Membrane Ruffle Membrane Presynapse	Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Polysomal Ribosome
	Molecular Function	Protein Binding ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity Phosphatidylinositol-3,4-bisphosphate 5-kinase Activity	RNA Binding Structural Constituent Of Ribosome
	Biological Process	Phosphatidylinositol Biosynthetic Process Phagocytosis Regulation Of Phosphatidylinositol 3-kinase Signaling Synaptic Vesicle Exocytosis Phosphorylation Actin Cytoskeleton Organization Neutrophil Chemotaxis Adherens Junction Assembly Phosphatidylinositol Phosphate Biosynthetic Process Synaptic Vesicle Endocytosis Membrane Organization Clathrin-dependent Endocytosis Cell-cell Adhesion	Cytoplasmic Translation Translation
Pathways		Synthesis of PIPs at the plasma membrane SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Clathrin-mediated endocytosis	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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GWAS
Interacting Genes		18 interacting genes: AKT1 AKT2 AP1B1 AP2B1 ARF6 BTK CDH1 CDK5 HDHD2 ITGB1 LAPTM4B LRP2 NEDD4 PKD1 RPL36 SMURF1 SRC TLN2	12 interacting genes: APP APPL2 ARHGAP45 DAZAP1 DUX4 KLHL4 NR2C2 PIP5K1C PTEN RPL18A SHC2 TESC
Entrez ID		23396	25873
HPRD ID		05834	10201
Ensembl ID		ENSG00000186111	ENSG00000130255
Uniprot IDs		O60331	Q9Y3U8
PDB IDs		2G35 3H1Z 3H85	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP
Enriched GO Terms of Interacting Partners?
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