SIN3B and MXI1

Number of citations of the paper that reports this interaction (PubMedID 15467743)
6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		SIN3B	MXI1
Description		SIN3 transcription regulator family member B	MAX interactor 1, dimerization protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin X Chromosome Y Chromosome XY Body Nucleus Nucleoplasm Cytoplasm Sin3 Complex Autosome	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways		NoRC negatively regulates rRNA expression RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS			Birth weight ( 31043758) Cutaneous malignant melanoma ( 32341527) Diastolic blood pressure ( 30224653) Neutrophil count ( 29403010 32888494) Normalized brain volume ( 19010793) Platelet count ( 29403010) Refractive error ( 32231278) White blood cell count ( 29403010 32888494)
Interacting Genes		22 interacting genes: AURKA COPS2 GDF15 H3-4 HDAC1 HDAC9 IKZF1 IKZF4 MAD1L1 MXD1 MXI1 NR1D2 POR REST RNF220 SETDB1 SMARCA2 SMARCA4 SMARCB1 SMARCE1 TP53 ZBTB16	29 interacting genes: APP CALCOCO2 CYSRT1 EFEMP2 ENTPD5 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-7 MAX MDFI MYC NBPF19 NOTCH2NLA PEAR1 RPL23AP32 SIN3A SIN3B SMARCB1 SMC3 UBE2O USHBP1 ZNF655
Entrez ID		23309	4601
HPRD ID		09691	02486
Ensembl ID		ENSG00000127511	ENSG00000119950
Uniprot IDs		B7Z392 M0QYC5 O75182	A0A0S2Z3X5 P50539
PDB IDs
Enriched GO Terms of Interacting Partners?
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