KAZN and TXN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KAZN	TXN2
Description		kazrin, periplakin interacting protein	thioredoxin 2
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleoplasm Cytosol Cytoskeleton Nuclear Speck Desmosome	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Protein Binding	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein-disulfide Reductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding
	Biological Process	Keratinization	Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Xenobiotic Stimulus Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Cell Redox Homeostasis Response To Axon Injury
Pathways		Formation of the cornified envelope	Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronic pain ( 33685280) Chronotype ( 30696823) Conotruncal heart defects (inherited effects) ( 28468790) Copper levels ( 26025379) HDL cholesterol levels in HIV infection ( 33109212) Lean body mass ( 28552196) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Mercury levels ( 26025379) Moderate-to-late spontaneous preterm birth ( 31194736) Non-response to antidepressants and depression ( 27622933) Polycystic ovary syndrome (reproductive subtype) ( 32574161) Schizophrenia x sex interaction ( 34099189) Triacylglyceride levels ( 31551469) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)
Interacting Genes		20 interacting genes: ARID5A CELA2A CELA2B CLVS2 COIL CTRC DVL3 FBLIM1 FXR1 KIF1B LMO2 LZTS1 LZTS2 NPPA PPL PSMA1 TNS4 TSC1 TXN2 USP2	80 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 BHLHB9 C11orf49 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B DCTD DDIT3 ETHE1 FAM9B FHL5 FMNL2 GOLGA6L9 GPRASP2 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SUN2 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32
Entrez ID		23254	25828
HPRD ID		11122	07161
Ensembl ID		ENSG00000189337	ENSG00000100348
Uniprot IDs		Q674X7	Q99757
PDB IDs			1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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