FLT1 and KDR

  • Number of citations of the paper that reports this interaction (PubMedID 10865839)
  • 29
  • Data Source:
  • HPRD (in vivo)

FLT1

KDR

Description fms related receptor tyrosine kinase 1 kinase insert domain receptor
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute respiratory distress syndrome in sepsis ( 31982041)
  • Birth weight ( 31043758)
  • Body mass index ( 26426971)
  • Cognitive performance ( 19734545)
  • Coronary artery disease ( 32469254 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 23364394)
  • Myocardial infarction ( 33532862)
  • Refractive error ( 32231278)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Triglyceride levels ( 32203549)
Interacting Genes 33 interacting genes: ALOX5AP ARL2BP ATR CDK8 CRK CTNNB1 FLT3 FYN GRB2 HMGB1 KDR LATS2 MIPEP NCK1 NEDD4 NRP1 NRP2 PGF PIK3R1 PLCG1 PLCG2 PTK2 PTK2B PTPN11 RASSF9 SHC1 SHC2 SRPK1 STAT1 STAT3 VEGFA VEGFB YES1 68 interacting genes: ACP1 AIMP2 ALB ANXA5 ATR BMX BTRC CACNA1S CAV1 CBL CCDC88A CDH5 CHIC2 COL18A1 CRK CSF2RB CSNK1D CTNNB1 DNM2 DUSP19 FBXO25 FBXW11 FLT1 FLT4 FRS2 FYN GABARAP GNA11 GNAQ GRB10 GRB2 GSTA2 HSP90AA1 ILKAP IQGAP1 ITGB3 KIT MAPK1 NCK1 NRP1 P2RY2 PDCL3 PLCG1 PLCG2 PPM1A PPM1B PTPN11 PTPN12 PTPN6 PTPRR RASA1 SERPINF1 SH2D2A SHB SHC1 SHC2 SHOX2 SRC SRP72 STAT1 STYX SYNGAP1 TIMP3 UTP3 VEGFA VEGFC VEGFD YES1
Entrez ID 2321 3791
HPRD ID 01297 01867
Ensembl ID ENSG00000102755 ENSG00000128052
Uniprot IDs L7RSL3 P17948 P35968
PDB IDs 1FLT 1QSV 1QSZ 1QTY 1RV6 2XAC 3HNG 4CKV 4CL7 5ABD 5EX3 5T89 1VR2 1Y6A 1Y6B 1YWN 2M59 2MET 2MEU 2OH4 2P2H 2P2I 2QU5 2QU6 2RL5 2X1W 2X1X 2XIR 3B8Q 3B8R 3BE2 3C7Q 3CJF 3CJG 3CP9 3CPB 3CPC 3DTW 3EFL 3EWH 3KVQ 3S35 3S36 3S37 3U6J 3V2A 3V6B 3VHE 3VHK 3VID 3VNT 3VO3 3WZD 3WZE 4AG8 4AGC 4AGD 4ASD 4ASE 5EW3 5OYJ 6GQO 6GQP 6GQQ 6XVJ 6XVK
Enriched GO Terms of Interacting Partners?
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