FBXL7 and IMPDH2

FBXL7

IMPDH2

Description F-box and leucine rich repeat protein 7 inosine monophosphate dehydrogenase 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to drug ( 30420678)
  • Alzheimer's disease (late onset) ( 26339675)
  • Asthma (corticosteroid response) ( 24486069)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Diisocyanate-induced asthma ( 25918132)
  • Economic and political preferences (feminism/equality) ( 22566634)
  • Haemorrhoidal disease ( 33888516)
  • Obesity-related traits ( 23251661)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Pulse pressure ( 27841878)
  • Response to fenofibrate (total cholesterol levels) ( 27002377)
  • Subcortical volume (MOSTest) ( 32665545)
  • Systolic blood pressure ( 27841878)
  • Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
  • Visceral fat ( 22589738)
Interacting Genes 6 interacting genes: APP BIRC5 FBXL18 FCHO1 IMPDH2 TBC1D5 32 interacting genes: AGR2 AKT1 ALS2 AMT APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 FXR1 FXR2 IL1F10 KLF7 OGT PIAS4 POU6F2 PRMT1 PXMP2 PXN RAD54L2 RBM15B STAT3 SUMO2 SUMO4 TRAF2 UBQLN4
Entrez ID 23194 3615
HPRD ID 05740 00895
Ensembl ID ENSG00000183580 ENSG00000178035
Uniprot IDs Q9UJT9 A0A384N6C2 P12268
PDB IDs 1B3O 1NF7 1NFB 6I0M 6I0O 6U8E 6U8N 6U8R 6U8S 6U9O 6UA2 6UA4 6UA5 6UAJ 6UC2 6UDO 6UDP 6UDQ
Enriched GO Terms of Interacting Partners?
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