RTF1 and VPS39

		RTF1	VPS39
Description		RTF1 homolog, Paf1/RNA polymerase II complex component	VPS39 subunit of HOPS complex
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cdc73/Paf1 Complex	Cytoplasm Lysosomal Membrane Late Endosome Membrane AP-3 Adaptor Complex HOPS Complex Late Endosome Membrane Lysosomal HOPS Complex
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding RNA Polymerase II C-terminal Domain Phosphoserine Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Endodermal Cell Fate Commitment Blastocyst Growth Transcription Elongation From RNA Polymerase II Promoter Wnt Signaling Pathway Stem Cell Population Maintenance Positive Regulation Of Histone H3-K4 Methylation Histone H3-K4 Trimethylation	Intracellular Protein Transport Autophagy Endosome To Lysosome Transport Endocytic Recycling Endosomal Vesicle Fusion Autophagosome-lysosome Fusion Late Endosome To Lysosome Transport
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 30013184) Asthma ( 32296059) Coronary artery disease ( 29212778) Eosinophil percentage of granulocytes ( 27863252) Height ( 20881960) Itch intensity from mosquito bite ( 28199695) Ulcerative colitis ( 28067908)
Interacting Genes		4 interacting genes: APP SRPK2 TCEA1 VPS39	10 interacting genes: HOOK1 NUSAP1 OIP5 RAB7A RILP RTF1 SNW1 STAT3 TFIP11 VPS11
Entrez ID		23168	23339
HPRD ID		11071	10300
Ensembl ID		ENSG00000137815	ENSG00000166887
Uniprot IDs		Q92541	A0A024R9L9 Q96JC1
PDB IDs		2BZE 2DB9 3U1U 4L1P 4L1U 6TED	6ZE9
Enriched GO Terms of Interacting Partners?
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